Nootropil 800 mg: Advanced Cognitive Support for Brain Health
| Product dosage: 800mg | |||
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Synonyms
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Nootropil 800 mg contains the active pharmaceutical ingredient Piracetam, a well-established nootropic agent belonging to the racetam class. It is specifically formulated to support cognitive function by modulating neurotransmission and enhancing neuronal metabolism. This high-dose tablet is designed for therapeutic efficacy in managing cognitive decline associated with various neurological conditions. Clinical use is supported by decades of research and pharmacological data indicating its role in improving memory, learning capacity, and overall mental performance under medically supervised conditions.
Features
- Active ingredient: Piracetam 800 mg per tablet
- Pharmaceutical form: Film-coated tablet for optimized oral bioavailability
- Mechanism of action: Modulates glutamate and acetylcholine receptors; enhances neuronal membrane fluidity
- Half-life: Approximately 5 hours in adults with normal renal function
- Excretion: Primarily renal, unchanged
- Prescription status: Available by prescription in most jurisdictions
Benefits
- Enhances synaptic plasticity and neurotransmission, supporting learning and memory consolidation.
- May improve cognitive performance in patients with mild to moderate cognitive impairment.
- Supports functional recovery in post-stroke aphasia and cortical myoclonus when used adjunctively.
- Promotes neuronal energy metabolism through increased ATP turnover and oxygen utilization.
- Reduces mental fatigue and supports focus during cognitively demanding tasks under clinical guidance.
- Provides a well-tolerated option for long-term cognitive support with an established safety profile.
Common use
Nootropil 800 mg is primarily indicated for the management of cognitive disorders, including cortical myoclonus as either monotherapy or adjunct treatment. It is also used off-label or in specific regions for cognitive enhancement in age-related memory decline, dyslexia, and sickle cell anemia-related vaso-occlusive complications. In clinical neurology and psychiatry, it may be used as supportive therapy for post-stroke recovery, particularly in cases involving aphasia or vertigo of central origin. Its application is always subject to regional licensing and prescribing guidelines.
Dosage and direction
The recommended adult dosage for cognitive disorders typically starts at 2.4–4.8 g daily, divided into two or three doses. Nootropil 800 mg tablets allow for flexible dosing—for example, 3–6 tablets per day depending on individual response and tolerability. Dosage should be individualized based on renal function, clinical indication, and patient response. Administration is oral, with or without food, though consistent timing is advised to maintain stable plasma concentrations. Dosage adjustments are necessary in patients with renal impairment. Treatment duration varies by indication and should be periodically reevaluated by a healthcare provider.
Precautions
Use with caution in patients with a history of bleeding disorders or those undergoing surgical procedures due to potential effects on platelet aggregation. Renal function should be assessed before and during treatment, especially in elderly patients. Discontinuation should be gradual to avoid withdrawal effects such as agitation or insomnia. Not recommended during pregnancy or lactation unless clearly necessary. Patients should avoid activities requiring mental alertness, such as driving, until individual response is established. Hemostatic parameters should be monitored in long-term users.
Contraindications
Hypersensitivity to Piracetam or any excipients in the formulation. Severe renal impairment (creatinine clearance <20 mL/min). Huntington’s chorea due to potential exacerbation of symptoms. Hemorrhagic diathesis or active bleeding. Use in children under 3 years of age is contraindicated. Patients with cerebral hemorrhage or major stroke should avoid use until stabilized.
Possible side effects
Common side effects (≥1/100 to <1/10) include nervousness, weight gain, drowsiness, and depression. Gastrointestinal disturbances such as nausea, abdominal pain, and diarrhea may occur. Less frequently (≥1/1,000 to <1/100), patients may experience hyperkinesia, asthenia, or insomnia. Rare side effects (<1/1,000) include anaphylactoid reactions, angioedema, and dermatological reactions. Side effects are generally dose-dependent and reversible upon discontinuation.
Drug interaction
May potentiate the effects of anticoagulants (e.g., warfarin), antiplatelet agents, and NSAIDs, increasing bleeding risk. Concomitant use with thyroid hormones may increase restlessness and irritability. Can enhance the effects of central nervous system stimulants. Caution is advised when co-administering with drugs that affect renal function. No significant interactions with cytochrome P450 substrates have been documented.
Missed dose
If a dose is missed, it should be taken as soon as remembered unless it is nearly time for the next scheduled dose. Doubling the dose to compensate for a missed one is not recommended. Maintain regular dosing schedule to ensure stable therapeutic levels. Consult a healthcare provider if multiple doses are missed or if uncertainty regarding dosing arises.
Overdose
Symptoms of overdose may include severe diarrhea, abdominal pain, and pronounced lethargy. In extreme cases, neurological symptoms such as agitation or confusion may occur. Management is supportive; there is no specific antidote. Gastric lavage may be considered if ingestion was recent. Hemodialysis can remove Piracetam efficiently due to its low protein binding and water solubility. Patients should seek immediate medical attention in case of suspected overdose.
Storage
Store at room temperature (15–30°C) in a dry place, protected from light and moisture. Keep the container tightly closed. Do not freeze. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.
Disclaimer
This information is intended for medical professionals and educated patients under medical supervision. It is not exhaustive and should not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider for personalized recommendations. Dosage and indications may vary by country; adhere to local prescribing information.
Reviews
Clinical studies and meta-analyses generally support the efficacy of Piracetam in cognitive enhancement and recovery post-cerebral incident, though results can be heterogeneous. Patient reports often note improvements in clarity of thought and memory recall, particularly in older adults with mild impairment. Some critics highlight the need for more robust, large-scale trials in non-specialized populations. Overall, it remains a frequently prescribed nootropic in many countries with a favorable risk-benefit profile when used appropriately.